Kratom (https://en.wikipedia.org/wiki/Mitragyna_speciosa) is a plant that produces two substances (mitragynine, 7-hydroxymitragynine aka 7-OH) that act like opioids. The pharmacology is relatively unusual, relative to most opioids, as the primary active substances in kratom also bind to serotonin and norepinephrine receptors; other alkaloids in the plant also act as ex. NMDA antagonists which may cause a dissociative experience (vaguely along the likes of ketamine, etc).
i have only taken xanax by rx and adhd meds … i say i am allergic to pot because i panic. always curious what is an opioid high like internally? i am a firefighter - and have administered narcan and the expected other things… but have never experienced opioids. thankfully. first wife had fentanyl and others due to chemo. she was in pain though. not “high”? (she died. cant really ask her …)
K2 (spice, etc) is the synthetic cannabinoids (https://m.psychonautwiki.org/wiki/Synthetic_cannabinoid), which are often fairly dangerous, but are unrelated to kratom.
Kratom (https://en.wikipedia.org/wiki/Mitragyna_speciosa) is a plant that produces two substances (mitragynine, 7-hydroxymitragynine aka 7-OH) that act like opioids. The pharmacology is relatively unusual, relative to most opioids, as the primary active substances in kratom also bind to serotonin and norepinephrine receptors; other alkaloids in the plant also act as ex. NMDA antagonists which may cause a dissociative experience (vaguely along the likes of ketamine, etc).
i have only taken xanax by rx and adhd meds … i say i am allergic to pot because i panic. always curious what is an opioid high like internally? i am a firefighter - and have administered narcan and the expected other things… but have never experienced opioids. thankfully. first wife had fentanyl and others due to chemo. she was in pain though. not “high”? (she died. cant really ask her …)