“I could care less” is almost always said sarcastically. A hallmark of sarcasm is saying the opposite of what you mean. So, a sarcastic “I could care less” implies they could not care less.

Right? Grown ups can be trusted to get their work done without someone watching them all the time. It’s small children who need constant supervision.

You don’t get it. Valve never has a business plan! It’s a hierarchyless place where everyone just moves their desk whenever and works on whatever they want. Plans? Who needs them!

According to Mayo Clinic, penicillin and amoxicillin also can make birth control less effective. But most other sources agree with you. I wonder if it’s relatively new information that those antibiotics don’t affect it or what.