Fusion 360 actually works under Linux with Bottles. Some other Autodesk products also have native Linux versions.

Slow computers and awful cheap Keyboards

I was talking about Mesa not the Nvidia open source drivers. I should have worded it differently

If you want to use Wayland without having to tweak lots of things or use weird hacks then Nvidia isn’t an option.

Also in my experience the open source drivers nowadays have better performance and support than the proprietary Nvidia drivers

Should work out of the box, if you want a better experience I would definitely recommend an AMD gpu. Nvidia drivers are a huge mess on Linux since Nvidia actively refuses to support Linux